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Strength: 325 mg / 10 mg
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hydrocodone 10 mg acetaminophen
hydrocodone 10 mg acetaminophen is a semisynthetic narcotic analgesic and antitussive with multiple actions qualitatively similar to those of codeine. Most of these involve the central nervous system and smooth muscle. The precise mechanism of action of hydrocodone and other opiates is not known, although it is believed to relate to the existence of opiate receptors in the central nervous
Therapeutic:allergy, cold, and cough remedies (antitussive), opioid analgesics Pharmacologic: opioid agonists/nonopioid analgesic combinations Schedule II (Zohydro ER)III (in combination)
Pregnancy Category C For information on the acetaminophen and ibuprofen components of these formulations.
Analgesic—2.5– 10 mg q 3– 6 hr as needed; if using combination products, acetaminophen dosage should not exceed 4 g/day and should not exceed 5 tablets/day of ibuprofen-containing products; Antitussive—5 mg q 4– 6 hr as needed; Extended release—10 mg q 12 hr; mayqas needed in increments of 10 mg q 12 hr q 3– 7 days.
Analgesic (1– 13 yr)—0.1– 0.2 mg/kg q 3– 4 hr. Antitussive — 0.6 mg/kg/day divided q 6– 8 hr; (maximum doses 2 yr: 1.25 mg/dose; 2– 12 yr: 5 mg/dose; 12 yr: 10 mg/dose)
Adverse Reactions/Side Effects
Noted for hydrocodone only; see acetaminophen/ibuprofen monographs for specific
information on individual components CNS: confusion, dizziness, sedation, euphoria, hallucinations, headache, unusual dreams.EENT: blurred vision, diplopia,miosis. Resp: respiratory depression. CV: hypotension, bradycardia. GI:constipation,
dyspepsia, nausea, vomiting. GU: urinary retention. Derm: sweating. Misc: physical dependence, psychological dependence, tolerance.